The impact of dialysis therapy on selected spirometric parameters in patients with end-stage renal failure. Evaluation of lung functions in patients treated with haemodialysis

Witold Rongies, Agata Młynarska, Tadeusz Przybyłowski, Włodzimierz Dolecki, Monika Lewandowska, Iza Korabiewska, Janusz Sierdziński, Justyna Choromańska

W. Rongies, A. Młynarska, T. Przybyłowski, W. Dolecki, M. Lewandowska, I. Korabiewska, J. Sierdziński, J. Choromańska – Ocena wybranych parametrów spirometrycznych w grupie pacjentów przewlekle dializowanych z powodu schyłkowej niewydolności nerek. Ocena wydolności oddechowej pacjentów leczonych przewlekłymi dializami. FP 2013; 13(3); 14-21

Abstract

lntroduction: Haemodialysis is used in the treatment of both acute and chronic renal failure as well as in some cases of poisoning. The purpose of haemodialysis is to clear the blood of toxic substances. During a haemodialysis session the body also receives substances necessary for regenerating its buffers and for the compensation of metabolic acidosis, and excess wafer is removed from the body. Despite these beneficial outcomes, most dialysis patients report subjective fatigue at the end of a session which can manifest itself an impairment of respiratory parameters. Material and methods: The study enrolled 21 chronic dialysis patients. The study procedures consisted in carrying out a forced spirometry procedure immediately before a dialysis session and 15 minutes after completion of the session. Results: All spirometric parameters assessed in the study group of 21 patients did not change significantly after a dialysis session. There were slight improvements in FEF50 and FEF25. FVC showed mild deterioration. None of the differences was statistically significant. At the same time, there was a statistically significant correlation between the degree of dehydration (loss of body weight during dialysis) and FVC values (p<0.05). Conclusions: 1. A single dialysis session did not induce significant changes in selected respiratory parameters in the study group. 2. The observed subjective feeling of fatigue following a dialysis session in the study group was not caused by impaired respiratory function.

Key words:
spirometry, dialysis, end-stage renal failure, rehabilitation