Effect of ketogenic diet and aerobic exercise on glucose level in prediabetes female with normal weight: A randomized controlled trial

Mona Mohamed Abdelkhalek, Hend Reda Sakr, Hanaa Mohsen Abd -Elfattah, Fairouz Hatem Ameen

Mona Mohamed Abdelkhalek, Hend Reda Sakr, Hanaa Mohsen Abd -Elfattah, Fairouz Hatem Ameen – Effect of ketogenic diet and aerobic exercise on glucose level in prediabetes female with normal weight: A randomized controlled trial. Fizjoterapia Polska 2021; 21(3); 206-211

Abstract
Objectives. It is well known that Individuals with prediabetes have a high risk of developing type 2 diabetes. This study aimed to compare the effect of combination of ketogenic diet and aerobic exercise interventions versus ketogenic diet alone on the glucose level in prediabetes female with normal weight. Methods. A total of sixty volunteer prediabetes females with normal body mass index (BMI) from 20-25 kg/m2 their age ranged from 40-60 years old, randomly divided into two equal groups and were recruited for a three-month trial. Group (I) (n = 30) treated by continuous aerobic exercise in form of treadmill 5 sessions per week and ketogenic diet. Group (II) (n = 30) treated by ketogenic diet alone. The primary outcome was the fasting plasma glucose and glycated hemoglobin while the secondary outcome was   body mass index and waist circumference. The outcome measures were measured before and after intervention for both groups. Results. Comparing both groups post-treatment revealed that there was significant improvement in fasting plasma glucose and glycated hemoglobin in favor of Group (I). Conclusion. combined continuous aerobic exercise and ketogenic diet improve glucose level in prediabetes female through decrease fasting plasma glucose and glycated hemoglobin.
Key words:
Prediabetes, Ketogenic diet, Aerobic exercise, Fasting plasma glucose, Glycated hemoglobin
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