The use of botulinum toxin in clinical practice

Olga Wolska, Wojciech Kiebzak, Wiesław Tomaszewski, Ireneusz Kowalski, Mariusz Majewski, Józef Szarek, Katarzyna Zaborowska-Sapeta

Olga Wolska, Wojciech Kiebzak, Wiesław Tomaszewski, Ireneusz Kowalski, Mariusz Majewski, Józef Szarek, Katarzyna Zaborowska-Sapeta – The use of botulinum toxin in clinical practice. Fizjoterapia Polska 2008; 8(2); 105-114

Abstract
Botulinum toxin is increasingly used in clinical practice as a basic or adjunctive agent in many fields modern medicine. In the field of rehabilitation of the musculoskeletal system, the introduction of botulinum toxin has opened new unexpected therapeutic avenues. This method broadens the possibilities for therapeutic intervention of doctors and physiotherapists, for whom complete recovery or improvement of the patient’s overall physical capacity is the measure of success. Because of its effectiveness and high safety for the patient, it is considered to be a modern and promising medicinal agent. The possibility of applying botulinum toxin selectively and, at the same time, precisely makes for a good clinical effect, while an appropriate pharmacological safety margin is also maintained. Although the range of indications is broad, it is in the treatment of spasticity of particular muscle groups who received the treatment as quickly as possible. Absolute contraindications include: myasthenia gravis, myasthenic syndrome, blood coagulability disorders. The most serious relative contraindications are pregnancy and breast-feeding. Intensive clinical research as well as numerous scientific meetings are making it possible for the method to gain more popularity and also to the clinical experience. Current standards of botulinum toxin use have been elaborated and published by an interdisciplinary group of experts. These standards are guidelines for practicing physicians. The author’s experience and available literature have served to present a state-of-the-art review of the use of botulinum toxin in clinical practice.
Key words:
spasticity, botulinum toxin, cerebral palsy
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Biofeedback Electromyography Training Versus Botulinum Toxin A on Synkinesis and Facial Asymmetry in Bell’s Palsy

Sarah G. Mohamed, Gehan M. Ahamed, Walaa M. Abd El Aziz, Amr M. Al-Said, Abeer Elwishy

Sarah G. Mohamed, Gehan M. Ahamed, Walaa M. Abd El Aziz, Amr M. Al-Said, Abeer Elwishy – Biofeedback Electromyography Training Versus Botulinum Toxin A on Synkinesis and Facial Asymmetry in Bell’s Palsy. Fizjoterapia Polska 2019; 19(3); 118-125

Abstract
Objective. To compare the effect of biofeedback electromyography training versus botulinum toxin A versus selected program of exercise on Synkinesis and facial asymmetry in Bell’s palsy. Methods. 45 patients with moderate facial synkinesis were divided randomly into three groups. All participants were evaluated using Sunnybrook facial grading system (FGS) and House Brackmann scale. The first group consisted of fifteen patients were received EMG biofeedback training for facial muscles. Second group consisted of fifteen patients were received a single dose of BTX-A injection for the management of synkinesis. And third group consisted of fifteen patients were received selected program of exercise for facial synkinesis.
Results. There was a significant increase of FGS measurement was in all the three groups between pre and post measurements but first group showed the more evidence of improvement. There was significant decrease HBS measurement of was in all the three groups between pre and post measurements while there was no significant difference between the three groups according to HBS measurement.
Conclusion. EMG biofeedback training therapy is as effective as the botulinum toxin A injection in reducing synkinesis and recovery of facial symmetry in Bell’s palsy. Our results may support interrelation between biofeedback training and improvement of voluntary movement of facial muscle and synkinasis. And also may support interrelation between BTX-A injection and facial symmetry.

Key words:
Bell’s palsy, EMG Biofeedback, Botulinum toxin, Synkinesis

 

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