Ireneusz Jurczak, Katarzyna Dudek, Ksenia Jurczak, Robert Irzmański

I. Jurczak, K. Dudek, K. Jurczak, R. Irzmański – Impact of controlled physical exercise on NT-proBNP level and ejection fraction in patients with acute coronary disease – original paper. FP 2016; 16(3); 58-66

Abstract
Purpose. Assess the effect of a controlled physical training on the level of NT-pro BNP and left ventricular ejection fraction depending on the time and type of physical exercise.
Methods. Eighty-three patients were included in the study. Two groups participated in interval training on a cycle ergometer and exercise improving general physical. Control Group participated in exercise improving general physical only. The immunoenzymatic test for qualitative determination of the NT – proBNP level and echocardiographic examination was performed in all groups.
Results. The authors observed changes in NT-proBNP level testing and echocardiographic examination. In the group I, after a 2-week training, the NT-proBNP value decreased by 13.2%. In the same group, mean EF values were significantly increased, from 51.23% to 51.95%. In the group II a 29% reduction of the NT-pro BNP level was observed. EF values were significantly increased, from 50.62% to 51.69%. As for final NT-proBNP values in the control group, a decrease of the peptide level by 3.9% was observed, compared to initial values. In the same group, a non-significant increase of the EF value was observed, from 47.06% to 47.13%
Conclusions. Findings of the studies confirm that cardiac rehabilitation decrease of the NT-proBNP level and improves LVEF in patients with acute coronary disease.

Key words:
cardiac rehabilitation, natriuretic peptide, ejection fraction, acute coronary disease

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