Ashwinkumar Chandrashekarapuram Swaminathan, Rajkumar Rajamanickam, Anurag Pathak,Vikas Soni, Ibnu Noufal Kambitta Valappil, Kumaran Badri, Debajit Karmakar,Ethiraj Balaji, Robert Çitozi, Vlad Adrian Geantă
Ashwinkumar Chandrashekarapuram Swaminathan et al. – Impact of yoga and music therapy on C-reactive protein levels in hypertensive middle-aged men: a single-group quasi-experimental study – Fizjoterapia Polska 2025; 25(1); 349-355
DOI: https://doi.org/10.56984/8ZG007DJX8D
Abstract
Background. Increased levels of C-reactive protein (CRP) are linked to a higher risk of cardiovascular complications in individuals with hypertension. While both yoga and music therapy have demonstrated independent cardiovascular benefits, their combined impact on inflammatory markers remains insufficiently studied.
Objective. This study aimed to assess the effects of a 12-week integrated yoga and music therapy program on inflammatory markers (hs-CRP, IL-6, TNF-α) and blood pressure in middle-aged men with hypertension.
Methods. A quasi-experimental pre-post design was employed, involving 36 hypertensive men (mean age 42.4 ± 6.41 years) who engaged in a structured yoga and music therapy regimen for 12 weeks. Key outcome measures included variations in inflammatory biomarkers (hs-CRP, IL-6, TNF-α) and blood pressure readings.
Results. The intervention led to significant decreases in inflammatory markers: hs-CRP (−1.50 ± 0.3 mg/L, p < 0.001), IL-6 (−1.56 ± 0.3 pg/mL, p < 0.001), and TNF-α (−4.12 ± 0.65 pg/mL, p < 0.001). Furthermore, notable reductions in blood pressure were observed: systolic (−11.59 ± 1.8 mmHg, p < 0.001) and diastolic (−5.06 ± 1.2 mmHg, p < 0.001). Effect sizes for all measured outcomes were substantial (0.71–0.78).
Conclusion. The findings suggest that a combined yoga and music therapy intervention can significantly lower both inflammatory markers and blood pressure in hypertensive middle-aged men. This holistic approach may serve as a valuable complementary strategy in the management of hypertension and inflammation-related cardiovascular risks.
Key words
yoga therapy, music therapy, hypertension, C-reactive protein, inflammatory markers, blood pressure, middle-aged men, complementary therapy