Impact of yoga and music therapy on C-reactive protein levels in hypertensive middle-aged men: a single-group quasi-experimental study

Ashwinkumar Chandrashekarapuram Swaminathan, Rajkumar Rajamanickam, Anurag Pathak,Vikas Soni, Ibnu Noufal Kambitta Valappil, Kumaran Badri, Debajit Karmakar,Ethiraj Balaji, Robert Çitozi, Vlad Adrian Geantă

Ashwinkumar Chandrashekarapuram Swaminathan et al. – Impact of yoga and music therapy on C-reactive protein levels in hypertensive middle-aged men: a single-group quasi-experimental study –  Fizjoterapia Polska 2025; 25(1); 349-355

DOI: https://doi.org/10.56984/8ZG007DJX8D

Abstract
Background. Increased levels of C-reactive protein (CRP) are linked to a higher risk of cardiovascular complications in individuals with hypertension. While both yoga and music therapy have demonstrated independent cardiovascular benefits, their combined impact on inflammatory markers remains insufficiently studied.
Objective. This study aimed to assess the effects of a 12-week integrated yoga and music therapy program on inflammatory markers (hs-CRP, IL-6, TNF-α) and blood pressure in middle-aged men with hypertension.
Methods. A quasi-experimental pre-post design was employed, involving 36 hypertensive men (mean age 42.4 ± 6.41 years) who engaged in a structured yoga and music therapy regimen for 12 weeks. Key outcome measures included variations in inflammatory biomarkers (hs-CRP, IL-6, TNF-α) and blood pressure readings.
Results. The intervention led to significant decreases in inflammatory markers: hs-CRP (−1.50 ± 0.3 mg/L, p < 0.001), IL-6 (−1.56 ± 0.3 pg/mL, p < 0.001), and TNF-α (−4.12 ± 0.65 pg/mL, p < 0.001). Furthermore, notable reductions in blood pressure were observed: systolic (−11.59 ± 1.8 mmHg, p < 0.001) and diastolic (−5.06 ± 1.2 mmHg, p < 0.001). Effect sizes for all measured outcomes were substantial (0.71–0.78).
Conclusion. The findings suggest that a combined yoga and music therapy intervention can significantly lower both inflammatory markers and blood pressure in hypertensive middle-aged men. This holistic approach may serve as a valuable complementary strategy in the management of hypertension and inflammation-related cardiovascular risks.
Key words
yoga therapy, music therapy, hypertension, C-reactive protein, inflammatory markers, blood pressure, middle-aged men, complementary therapy
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Effect of aerobic exercise on inflammation and sex hormones in obese polycystic ovarian syndrome women: A randomized controlled study

Doaa A. Abd El Aziz, Fahima M. Oqeel, Magid M. Labib, Amel M. Yousef

Doaa A. Abd El Aziz, Fahima M. Oqeel, Magid M. Labib, Amel M. Yousef – Effect of aerobic exercise on inflammation and sex hormones in obese polycystic ovarian syndrome women: A randomized controlled study. Fizjoterapia Polska 2021; 21(4); 204-209

Abstract
Purpose. This study aimed to investigate the effect of aerobic exercise on inflammation and female sex hormones in obese PCOS women. Materials and methods. Forty volunteer obese PCOS women were participated in this study, their ages ranged from 20 to 35 years and body mass index (BMI) ranged from 30 to 34.9 kg/m2, they randomly divided into two equal groups in numbers; group A, followed diet control therapy and group B, participated in an aerobic exercise three times per week and followed the same diet control therapy as group A. Both groups were evaluated before and after therapy (12weeks) through measuring their BMI, C-reactive protein (CRP), luteinizing hormone (LH), follicular stimulating hormone (FSH), LH/FSH ratio and modified Ferryman–Gallwey (mFG) scoring system for hirsutism Results. showed that there was a statistically significant difference (P < 0.05) in both groups (A&B) in BMI, LH, FSH, LH/FSH ratio, CRP and mFG in favor to group (B) after therapy (12 weeks). Conclusions. revealed that aerobic exercises are effective in decreasing weight and inflammation which lead to improve fertility by improving female sex hormonal variables.
Key words:
Polycystic ovarian syndrome, Aerobic exercise, Follicular stimulating hormone, luteinizing hormone, C-reactive protein
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Impact of pulsed electromagnetic on chronic pelvic inflammatory disease: A randomized controlled trial

Eman Abdelfatah Mohamed Elhosary, Hamada Ahmed Hamada, Mahmoud Ewidea, Zizi M. Ibrahim

Eman Abdelfatah Mohamed Elhosary, Hamada Ahmed Hamada, Mahmoud Ewidea, Zizi M. Ibrahim – Impact of pulsed electromagnetic field on pain level in Females with chronic pelvic inflammatory disease: A randomized controlled trial. Fizjoterapia Polska 2020; 20(3); 116-120

Abstract
Purpose. Pelvic inflammatory disease (PID) is an infection-induced inflammation of the female upper reproductive tract some cases not respond to medical treatment, the aim of the study to detect the effect of pulsed electromagnetic (PEMF)in treatment of chronic pelvic inflammatory disease. Materials and Methods. this study was designed as single blind randomized controlled trial. Forty females complain from PID, their age ranged from (20-40) years and their body mass index (BMI) not exceeds 30 kg/m², they and were randomly assigned into 2 equal groups: Study group (A) received oral antibiotic (doxycycline100 mg) twice daily for 7 days in addition to PEMF for1 hour, 3 times per week for 12 sessions with 50 Hz in frequency and 60 G in intensity. Control group (B) received routine medical treatment by oral antibiotic (doxycycline100 mg) twice daily for 7 days. Both groups were assessed by present pain intensity scale, estimation of C-reactive protein and ESR level in blood before the treatment and after 12 sessions of PEMF. Results. There were significant differences in pain scores presented by Mean Difference (MD) and 95% Confidence Interval(CI) (MD 2; 95%CI 1.8 to 2.21), ESR (MD 16.75; 95%CI 13.973 to 19.52) and CRP (MD 35.8; 95%CI 31.97 to 39.63) between the both groups. The significant improvement from pretreatment to post treatment, was seen in all dependent variables at study group (p < 0.05) and in pain severity and CRP in control group. Conclusion. Pulsed electromagnetic yields improvement in pain and decrease in inflammation measured by decrease inflammatory markers in the treatment of pelvic inflammatory disease.
Key words:
Pelvic inflammatory disease, Pulsed electromagnetic field, ESR, C-reactive protein
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