The effect of nitrate supplementation on exercise performance – an umbrella review of meta-analyses

Maisarah Mohd Saleh, Roxana Dev Omar Dev, Adam Linoby, Iqbal Norhamazi, Rozella Ab Razak, Azrisan Ahsan, Norhasmah Sulaiman

Ashwinkumar Chandrashekarapuram Swaminathan et al. – The effect of nitrate supplementation on exercise performance – an umbrella review of meta-analyses –  Fizjoterapia Polska 2025; 25(1); 356-363

DOI: https://doi.org/10.56984/8ZG007D9ZWE

Abstract
There is often a lack of agreement in the outcomes of meta-analyses exploring the performance-boosting effects of nitrate supplements. The present study conducts a detailed assessment of existing meta-analyses on the impact of dietary nitrate on exercise efficiency, applying a comprehensive review strategy. Research articles were sourced from electronic databases, including EBSCOhost, PubMed, Scopus, and Web of Science. The methodological rigor of these meta-analyses was evaluated using established tools—AMSTAR 2—and was found to be moderate on average. The findings indicate that nitrate supplementation leads to a small but significant enhancement in exercise performance by 0.10% compared to a placebo. However, the benefit is specific to aerobic endurance, which saw an improvement of 0.11%, while no significant effects were observed for muscle endurance, strength, or anaerobic capacity. Notably, muscle endurance performance tends to improve with nitrate supplementation by 0.31% (P = 0.07). In summary, the current work indicates that nitrate supplementation can improve exercise performance, with the magnitude of the effect being greater in aerobic endurance compared to anaerobic performance.
Key words
nitrate, supplementation, exercise performance, umbrella review, meta-analysis
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Evaluation of menstrual cycle irregularities among mature women running recreationally

Barbara Górska, Izabela Zbrońska


Barbara Górska, Izabela Zbrońska – Evaluation of menstrual cycle irregularities among mature women running recreationally. Fizjoterapia Polska 2022; 22(2); 6-16

Streszczenie
A group of 106 mature female recreational runners were studied in the context of their menstrual irregularities due to cycle length, menstrual cycle loss. Influencing factors such as running intensity, years of training, BMI, vitamin D intake were considered. The hormonal fluctuations associated with menstrual irregularities over a woman’s lifetime can lead to the initiation of a health cascade and the onset of many serious diseases such as osteoporosis and cardiovascular episodes. Observing the menstrual cycle in women who train to run provides insight into early indicators of more serious health problems that may affect them. Polymenorrhoea, oligomenorrhoea, secondary amenorrhea as well as amenorrhea of less than 3 months can be observed among mature women running recreationally. The irregularities examined may have important implications for women’s overall health. Influencing factors: BMI – does not correlate with menstrual interruption and secondary amenorrhea; training intensity – does not correlate with secondary amenorrhea, i.e., no relationship with distance run, number of training days, or length of training per day; years of training – correlates with longer menstrual interruption and secondary amenorrhea; vitamin D – correlates with number of cycles per year.
Słowa kluczowe
menstrual cycle irregularities, amenorrhea, oligomenorrhoea, BMI, supplementation
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