Tag: irisin

Učinak umjereno intenzivnog intervalnog treninga (MIIT) i visoko intenzivnog intervalnog treninga (HIIT) na razine irizina kod pretilih štakora

Didib Riwayadi, Rachmah Laksmi Ambardini, Panggung Sutapa, Deni Hardianto, Syed Kamaruzaman Syed Ali, Manil Karakauki, Sherif Juniar Aryanto, Kukuh Wahyudin Pratama, Danarstuti Utami, Agus Kristianto

Didib Riwayadi et al. – Moderate Intensity Interval Training (MIIT) and High Intensity Interval Training (HIIT) exercise therapy against irisin levels in obesity –  Fizjoterapia Polska 2024; 24(4); 136-139

DOI: https://doi.org/10.56984/8ZG01A8Q3S7

Sažetak

Pozadina. Pretilost može uzrokovati fiziološke poremećaje, a ovi poremećaji povezani su s ulogom irizina. Redovita, odmjerena tjelovježba jedan je od pristupa u borbi protiv pretilosti. Ciljevi ove studije bili su (1) utvrditi učinak razine irizina u vježbama s modelima umjereno intenzivnog intervalnog treninga (MIIT) i visoko intenzivnog intervalnog treninga (HIIT) kod pretilih štakora.
Metode. Ovo istraživanje je eksperimentalna laboratorijska studija s dizajnom pretest-posttest s kontrolnom skupinom. Provedeno je u bioscijenskom laboratoriju Sveučilišta Brawijaya u Malangu. Uzorak je obuhvatio 27 pretilih mužjaka Wistar štakora, podijeljenih u 9 štakora MIIT grupe, 9 HIIT štakora i 9 kontrolnih štakora. Intervencija vježbanjem trajala je 6 tjedana, 4 puta tjedno. Intenzitet MIIT-a bio je 60–80 % osnovne razine sposobnosti, HIIT-a 90–100 %, a razine irizina određene su krvnim testovima korištenjem imunoenzimskog testa (ELISA). Za analizu podataka korišten je Anova test i Tukey post-hoc analiza sa značajnom razinom 0,01.
Rezultati. Rezultati su pokazali da nema značajnih razlika u razinama irizina (p = 0,507). HIIT razina irizina bila je niža od MIIT-a (p = 0,932) i Kontrole (p = 0,491), a nije bilo razlike u razini irizina između MIIT-a i kontrolne grupe (p = 0,708).

Ključne riječi
pretilost, MIIT, HIIT, irizin

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Acute aerobic Exercise Induced Irisin Release in Type 2 Diabetic patients: Randomized Clinical Trial

Basant Hamdy Elrefaey, Heba Ali Abd EL-Ghaffaar,Doaa Mohammed Mahmoud Allam, Mohamed Abd EL-Motaal Safa

Basant Hamdy Elrefaey, Heba Ali Abd EL-Ghaffaar,Doaa Mohammed Mahmoud Allam, Mohamed Abd EL-Motaal Safa – Acute aerobic Exercise Induced Irisin Release in Type 2 Diabetic patients: Randomized Clinical Trial. Fizjoterapia Polska 2019; 19(4); 58-63

Abstract
Background. Type 2 diabetic subjects have lower irisin level, irisin discovery has provides a modern track for energy homeostasis and opens a chance for development of curative components to manage metabolic disorders. Purpose: The Objective of this study was to explore acute irisin response to two different types of aerobic training modes in type 2 diabetics. Methods. Thirty-one type 2 diabetic patients aged between 45 and 60 years, were randomly assigned into two exercise groups: (EX1) group (n = 16) who received continuous aerobic exercise and (EX2) group (n = 15) who received interval aerobic exercise. The program in both groups was in the form of treadmill walking for 60 min. Blood collection of primary outcome (irisin) and assessment of oxygen saturation (SpO2) and heart rate (HR) were done at baseline and immediately after single aerobic bout. 6MWT was used to determine individual training intensity for each subject.
Results. After single aerobic exercise bout, there was significant improvement in irisin in both groups (p = 0.0001, 0.01 respectively), increase in HR (p = 0.0001 in both groups) & decrease in SPO2 in EX1 (p = 0.002) with non significant difference between groups in the mean values of HR & SpO2 post exercise (p < 0.05),however there was significant difference between groups in the mean values of irisin level favoring EX1 group (p = 0.03). Conclusion. Acute aerobic exercise is effective in improving irisin level in type 2 diabetes and the superiority in irisin improvement was to continuous exercise than interval exercise. Further studies are required to discover irisin response in type 2 diabetes with different types of exercise protocols rather than aerobics.

Key words:
acute, aerobic exercise, irisin, type 2 diabetes

 

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