Background. The objective of this study was to observe and evaluate development of premature baby using Prechtl’s method of assessment of general movements. Qualitative assessment of spontaneous motor activity can be additional to neurological examination as well as determine objective prognosis for future psychomotor development and indicate abnormal movement patterns. It also gives possibility to begin appropriate stimulation of development. Material and methods. Motor spontaneous activity was assessed in case of premature baby born in 25 week of gestation with extremly low birth weight (670 g). We assessed changes in quality of general movements based on video recordings done in expected birth date, 1-st, 2-nd, 4-th, 6-th and 12-th week of corrected age. After 15 months of life we calculate motor quotient. Results. Evaluation of repeated video recordings indicated predominant poor repertoire character of spontaneous motor activity. That also indicated real danger for future development and determine decision to start therapy. Next recording made in 52 week of gestational age showed lack of normal fidgety movements, but equally appeared voluntary movements and manipulation. Conclusions. Relay on Prechtl’s method we indicate abnormal motor activity during firsts weeks of life. We decide to began therapy with continuous observation of spontaneous motor activity. Hypothetically we minimized danger of developmental delay. Assessment of general movement enables early detection of abnormal motor patterns and provides realistic prognosis for future development as well as minimize possible developmental menace. There is an urgent need to observe later development of pre-mature babies, esspecially those with extremely low birth weight and immature nervous and other systems.