Tag: inflammation

Physical exercise and curcumin supplementation have the potential to reduce pain intensity in women with primary dysmenorrhea: Systematic review

Dhea Regita Sastika Putri, Budi Prasetyo, Annis Catur Adi, Anton Komaini, Novadri Ayubi

Dhea Regita Sastika Putri, Budi Prasetyo, Annis Catur Adi, Anton Komaini, Novadri Ayubi – Physical exercise and curcumin supplementation have the potential to reduce pain intensity in women with primary dysmenorrhea: Systematic review. Fizjoterapia Polska 2023; 23(5); 185-190

DOI: https://doi.org/10.56984/8ZG20BSbq

Abstract
This review aims to highlight the potential of physical exercise and curcumin supplementation in reducing pain intensity in women with primary dysmenorrhea. This research uses a systematic review method. Studies were identified through Proquest, Pubmed, ScienceDirect, and PMC Europe electronic databases. The inclusion criteria in this study were international journals that focused on discussing aerobic exercise, stretching, core strengthening, Zumba, and FITT as treatment methods for PD, as well as articles that discussed the efficacy of curcumin as a PD treatment. The exclusion criteria in this study were international journals that had been published in the last 5 years and articles that were not relevant to PD treatment. For standard operationalization, this Study follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Based on the results of the review, physical exercise such as aerobic exercise, treadmill, Zumba, squatting exercise, and therapeutic exercise which is done regularly has the potential to reduce the intensity of menstrual pain. Furthermore, curcumin supplementation at a dose of 500-1000 mg can help reduce complaints of primary dysmenorrhea by inhibiting the cyclooxygenase (COX) reaction so that it can reduce inflammation and inhibit uterine contractions which cause menstrual pain.

Keywords
physical exercise, curcumin, inflammation, primary dysmenorrhea

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Aspects of spontaneous activity in afferent nerve fibres

Maciej Pawlak, Bartosz Trawiński

Maciej Pawlak, Bartosz Trawiński – Aspects of spontaneous activity in afferent nerve fibres. Fizjoterapia Polska 2011; 11(3); 185-198

Abstract
In some situations, nerve cells display peculiar behaviour, referred to as spontaneous activity. It consists in generating spontaneous action potentials, which are not directly triggered by an external factor. They are most frequently recorded at nerve endings located in an area of damaged tissue and subject to sensitisation or a traumatic neuroma.Spontaneous activity of nerve fibres may vary in form and intensity. From the clinical viewpoint, it is important to determine whether this activity still represents a physiological form of transferring information to the body or whether it is purely pathologic activity, carrying no information. This distinction becomes especially important in the case of slowly conducting nociceptive nerve fibres, which supply the central nervous system with information about strong stimuli acting on the tissue and events capable of inflicting tissue damage. The activity of this group of nerve fibres stimulates central structures of the nociceptive system, produces pain sensations and may cause hyperalgesia and allodynia.Research on spontaneous activity has special application for rehabilitation methods and physiotherapeutic activities in clinical practice. Such activity of neurons is capable of modulating patients’ thresholds for experiencing sensations, including pain, which may adversely affect their reception of the therapy.
Key words:
spontaneous activity, nerve fibre, Neuroma, Inflammation
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The effect of magnetic field on the signal transduction

Natalia Cichoń, Joanna Saluk, Sergiusz Miller, Elżbieta Miller

The effect of magnetic field on the signal transduction. FP 2014; 14(1); 50-58

Abstract

The therapy using the magnetic field has been known for centuries. Today it is a technique widely used in practice due to low harmfulness, wide applicability and good clinical outcomes with relatively low outlay. The biological effect of the magnetic field is related, inter alia, with analgesic and anti-inflammatory effect. The analgesic activity is primarily based on the endogenous opioid system. The magnetic field regulates opioid analgesic by affecting the calcium channels, and Ca2+ concentration. Furthermore, the magnetic field enhances the immune system affecting the inflammatory reactions. One of the mechanisms of anti-inflammatory effect of magnetotherapy may also be an antioxidant activity. The confirmation of the analgesic and anti-inflammatory effect of the magnetic field are clinical trials conducted in various institutions in the world. Have been documented, among others, studies which used magnetic therapy in the treatment of carpal tunnel syndrome, diabetic neuropathy and fibromyalgia. The aim of this study is to present the current state of knowledge on the mechanisms of action of analgesic and anti-inflammatory magnetic field.

Key words:
magnetic fields, analgesia, inflammation

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