Tag: laser biostimulation

Laser therapy: a physiotherapeutic fetish?

Krzysztof Spodaryk, Edyta Mikołajczyk

Krzysztof Spodaryk, Edyta Mikołajczyk – Laser therapy: a physiotherapeutic fetish? Fizjoterapia Polska 2001; 1(1); 59-62

Abstract
Background. The authors have reviewed the literature on the impact of laser radiation on biochemical and physiological phenomena in animal models and in the human organism, and have analyzed reports on the clinical application of laser biostimulation. Analysis. The analysis included 46 publications, which resulted from the methodological assumptions made in the article. The issues discussed in detail include: 1) the impact of laser biostimulation on the process tissue healing, 2) the impact of laser biostimulation on pain perception, 3) the impact of laser biostimulation on the inflammatory process. Conclusion. A summation of the results indicates that despite the almost 30-year history of the application of the laser in physiotherapy, much remains unknown, and many areas of possible application of this physical stimulant are still unexplored.

Key words:
Laser Therapy, laser biostimulation, history of the application of laser

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The role of nitric oxide in the modulation of arterial smooth muscle contraction evoked by activation of adrenoreceptors during laser biostimulation

Magdalena Mackiewicz-Milewska, Jan Talar, Grzegorz Grześk, Leszek Szadujkis-Szadurski, Irena Bułatowicz, Zbigniew Śliwiński

Magdalena Mackiewicz-Milewska, Jan Talar, Grzegorz Grześk, Leszek Szadujkis-Szadurski, Irena Bułatowicz, Zbigniew Śliwiński – The role of nitric oxide in the modulation of arterial smooth muscle contraction evoked by activation of adrenoreceptors during laser biostimulation. Fizjoterapia Polska 2002; 2(2); 89-98

Abstract
Introduction. The mechanisms of action of laser biostimulation on tissue continues to be the object of scientific investigation. The positive impact of laser radiation of low and medium power on inhibiting vascular contraction has been proven. It remains unknown, however, exactly how this takes place. We investigated the role of nitric oxide in this process.Material and methods. An in vitro experiment was performed on isolated tail arteries of male Wistar rats. The arteries were first subjected to the effect of noradrenalin (NA) and phenylephrine (PHE), and then to the effect of laser radiation (10, 30 and 100 mW), Then an inhibitor of nitric oxide synthase was added to the incubation fluid, along with methylene blue, and the effects of laser radiation in these conditions were observed.Results. Laser radiation of 10, 30, and 110mW inhibits the vascular contraction reaction induced by NA and PHE. The addition of a nitric oxide inhibitor or a guanyl cyclase inhibitor (methylene blue) to the incubation fluid cancels the inhibitory effect of laser biostimulation on contraction. Conclusion. Our results imply that the inhibitory effect of laser biostimulation on vascular contraction is mediated by nitric oxide and its secondary transmitter, guanyl cyclase.

Key words:
laser biostimulation, vascular endothelium, Nitric Oxide, adrenoreceptors

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