Abstract

Problems and Purpose. A measurable physical exercise that follows the rules can improve physiological abilities. However, physical exercise that is not according to the rules, such as lack of recovery time caused by too frequent exercise, can increase the accumulation of free radicals in the body. In addition, the limited recovery time can also increase tissue damage to the muscles. Therefore, this study aims to determine the effect of differences in the frequency of physical exercise in one week on serum antioxidant levels and tissue damage.

Materials and methods. This study was experimental with a post-test-only control group design, with the sample being male Wistar rats. There were 24 male Wistar rats divided into four groups. In the control group, the rats were not given physical exercise. In experimental group 1, rats were given physical exercise 2 times a week. In experimental group 2, rats were given physical exercise 4 times a week. In group 3, rats were given physical exercise every day. Physical training was carried out for four weeks. Then, biomarkers of serum antioxidant levels (SOD, CAT, GPx) and muscle tissue damage biomarkers (LDH, IL-6, and CPK) were checked.

Results. Physical exercise 4 times a week and daily without sufficient recovery time can significantly reduce serum antioxidant levels and increase muscle tissue damage (p < 0.05).

Conclusion. Based on this study, physical exercise must be accompanied by sufficient recovery time to avoid decreased serum antioxidant levels and increased muscle tissue damage.

Key words: physical exercise, antioxsidant level, muscle damage