Effect of pulsed electromagnetic field on renal function in paracetamol-induced toxicity rat model

Mai M. Aboelhamd, Samir Algazzar, Samah Elattar, Amira Draz, Nesreen M. Elnahas


Mai M. Aboelhamd, Samir Algazzar, Samah Elattar, Amira Draz, Nesreen M. Elnahas – Effect of pulsed electromagnetic field on renal function in paracetamol-induced toxicity rat model. Fizjoterapia Polska 2022; 22(3); 38-43

Abstract
Purpose of the study. To evaluate the efficacy of extremely low frequency pulsed electromagnetic field (ELF-PEMF) on renal function following paracetamol induced toxicity rat model by improving renal function test (serum urea and creatinine level).
Methods. 22 rats of 10 ± 2 months old received a single dose of paracetamol (PC) (2 g/kg) Paramol® (500 mg/tablet) and subdivided into two groups randomly. Group A (control group): received only PC dose and group B (PEMF group): were exposed to ELF-PEMF at four frequencies (1, 10, 20, and 40 Hz) in three series, the transition period of each pulse train is 4 min, followed by 1 min of rest, each series is performed for 20 min, for a total of 60 min/daily applications for 4 weeks. Assessment was done by measuring renal function test (serum urea and creatinine level), first after the induction of PC toxicity, then after 4 weeks at the end of the experiment.
Results. This trial revealed a significant improvement in renal function in the PEMF group after the exposure to ELF-PEMF by showing a significant decline in both creatinine level (p = 0.001) and serum urea (p = 0.003). A significant reduction in both creatinine and serum urea at post treatment in compare to pre-treatment (P-value = 0.0001)
Conclusion. By evaluating the efficacy of ELF-PEMF in kidney toxicity rat model inducted by a toxic dose of paracetamol, we observed an obvious improvement in kidney function in the PEMF group.

Keywords
Pulsed electromagnetic field, renal function, paracetamol

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Effect of pulsed electromagnetic field versus interferential current on abdominal fat thickness in postnatal women

Menna Allah Y. Nasr Eldien, Khadiga S. Abd El Aziz, Mohamed A. Awad, Amir A. Gabr

Menna Allah Y. Nasr Eldien, Khadiga S. Abd El Aziz, Mohamed A. Awad, Amir A. Gabr – Effect of pulsed electromagnetic field versus interferential current on abdominal fat thickness in postnatal women. Fizjoterapia Polska 2021; 21(5); 144-151

Abstract
Objective. To compare the efficacy of the pulsed electromagnetic field and the interferential current effects on abdominal fat thickness in postnatal women.
Method. This study enlisted the participation of sixty obese postnatal multipara women, ages ranged between 30 and 40 years, body mass index ranged between 30 to 39.9 kg/m2, and they were chosen at least two years after the previous delivery. They were selected and equally divided at random into two groups (A&B). Group A (n = 30) was treated with pulsed electromagnetic field on the abdomen. Each session lasted about 20 minutes and was held three days per week for four weeks. Group B (n = 30) was treated with interferential current on the abdomen. Each session lasted about 20 minutes and was held three days per week for four weeks.
Body mass index was evaluated by weight and height scale, waist circumference was evaluated by tape measurement, abdominal subcutaneous fat thickness was evaluated by skin fold caliper, and blood lipid profile was measured in both groups before and after treatment.
Results: Within groups, there were significant reduction in BMI, WC, abdominal subcutaneous thickness, and blood lipids profile (TC, TG, LDL, and VLDL), and significant increase in HDL in both groups (A&B) post-treatment in compare to pre-treatment. Between groups, there were no significant differences in all measurement values between both groups (A&B) pre and post-treatment.
Conclusion: PEMF and IFC are safe and have the same effect in reducing BMI, WC, abdominal subcutaneous fat thickness, and blood lipids in postnatal women.
Key words:
pulsed electromagnetic field, interferential current, abdominal fat thickness, postnatal women, waist circumference
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Effect of Pulsed Electromagnetic Field on Walking Capacity in Patients with Peripheral Arterial Disease

Reham R. Mahmoud, Awny F. Rahmy, Mohamed G. Ibrahim, Abeer A. Farghaly

Reham R. Mahmoud, Awny F. Rahmy, Mohamed G. Ibrahim, Abeer A. Farghaly – Effect of Pulsed Electromagnetic Field on Walking Capacity in Patients with Peripheral Arterial Disease. Fizjoterapia Polska 2021; 21(3); 226-232

Abstract
Background. Peripheral arterial disease (PAD) is a common vascular disorder characterized by intermittent claudication with costly complications and marked reduction in functional capacity. The pulsed electromagnetic field (PEMF) has been used widely for different patient populations owing to its analgesic, anti-inflammatory, and angiogenetic effects, however, its use in the management of PAD has been recently introduced. Aim. this study aimed to assess the effect of PEMF on functional walking parameters in patients with PAD. Material and Methods. Sixty patients with PAD (Fontaine stage II), aged from 45-65 were divided into two groups A & B. Group (A) received pulsed electromagnetic field for 60 minutes/session, 3 sessions/week, and for 8 weeks plus drug treatment, whereas, group (B) only received the traditional drug treatment for 8 weeks. The endpoints of the study were claudication pain distance (CPD), maximal walking distance (MWD), claudication pain time (CPT), maximal walking time (MWT), and ankle-brachial index (ABI). Results. There were significant changes in all measured variables compared to the baseline in the two groups. There were significant differences between the two groups in CPD, MWD, CPT, MWT, and ABI in favor of the PEMF group (P < 0.05). Conclusion. PEMF could be an effective therapeutic modality that can help improve the functional walking capacity in patients with PAD (Fontaine stage II).
Key words:
Pulsed electromagnetic field, peripheral arterial disease, walking capacity, Intermittent claudication
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Impact of pulsed electromagnetic on chronic pelvic inflammatory disease: A randomized controlled trial

Eman Abdelfatah Mohamed Elhosary, Hamada Ahmed Hamada, Mahmoud Ewidea, Zizi M. Ibrahim

Eman Abdelfatah Mohamed Elhosary, Hamada Ahmed Hamada, Mahmoud Ewidea, Zizi M. Ibrahim – Impact of pulsed electromagnetic field on pain level in Females with chronic pelvic inflammatory disease: A randomized controlled trial. Fizjoterapia Polska 2020; 20(3); 116-120

Abstract
Purpose. Pelvic inflammatory disease (PID) is an infection-induced inflammation of the female upper reproductive tract some cases not respond to medical treatment, the aim of the study to detect the effect of pulsed electromagnetic (PEMF)in treatment of chronic pelvic inflammatory disease. Materials and Methods. this study was designed as single blind randomized controlled trial. Forty females complain from PID, their age ranged from (20-40) years and their body mass index (BMI) not exceeds 30 kg/m², they and were randomly assigned into 2 equal groups: Study group (A) received oral antibiotic (doxycycline100 mg) twice daily for 7 days in addition to PEMF for1 hour, 3 times per week for 12 sessions with 50 Hz in frequency and 60 G in intensity. Control group (B) received routine medical treatment by oral antibiotic (doxycycline100 mg) twice daily for 7 days. Both groups were assessed by present pain intensity scale, estimation of C-reactive protein and ESR level in blood before the treatment and after 12 sessions of PEMF. Results. There were significant differences in pain scores presented by Mean Difference (MD) and 95% Confidence Interval(CI) (MD 2; 95%CI 1.8 to 2.21), ESR (MD 16.75; 95%CI 13.973 to 19.52) and CRP (MD 35.8; 95%CI 31.97 to 39.63) between the both groups. The significant improvement from pretreatment to post treatment, was seen in all dependent variables at study group (p < 0.05) and in pain severity and CRP in control group. Conclusion. Pulsed electromagnetic yields improvement in pain and decrease in inflammation measured by decrease inflammatory markers in the treatment of pelvic inflammatory disease.
Key words:
Pelvic inflammatory disease, Pulsed electromagnetic field, ESR, C-reactive protein
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Treadmill weight-bearing exercise versus electromagnetic field on bone mineral density in women with osteoporosis secondary to aromatase inhibitors: A randomized controlled trail

Haidy Nadi Ashem, Amira Hussein Draz, Amr Almaz Abdel-aziem, Marwa Esmael Hasanin, Mohamed Abdelrahman

Haidy Nadi Ashem, Amira Hussein Draz, Amr Almaz Abdel-aziem, Marwa Esmael Hasanin, Mohamed Abdelrahman – Treadmill weight-bearing exercise versus electromagnetic field on bone mineral density in women with osteoporosis secondary to aromatase inhibitors: A randomized controlled trail. Fizjoterapia Polska 2019; 19(3); 138-143

Abstract
Background and objective. Aromatase inhibitor therapy for postmenopausal women with breast cancer is associated with a decrease in bone mineral density (BMD). Both Pulsed electromagnetic fields (PEMFs) and treadmill walking exercises have a positive effect on bone osteoporosis. So, this study aimed to evaluate the effect of PEMFs and treadmill weight bearing exercises on the BMD of the lumbar spine in women with osteoporosis secondary to adjuvant hormonal treatment with aromatase inhibitor.
Methods. A total of 45 female breast cancer patients with osteoporosis secondary to adjuvant aromatase inhibitor were randomly assigned into three equal groups. The control group received only pharmacological treatment (Bisphosphonates, Calcium and Vitamin D). In the other 2 groups, the same drug therapy was consolidated by a program of treadmill weight bearing exercises (treadmill exercise group; 30 min/session, 3 sessions/week), and PEMFs (PEMFs group; 30 min/session, 3 sessions/week). The BMD of the spinal vertebrae was assessed before and after 3 months of intervention by using the Dual energy X-rays (DEXA).
Results, The post value of the PEMFs group was significantly higher than those of the treadmill exercise group and the control group (p = 0.002, 0.001 respectively), and the post value of the treadmill exercise group was significantly higher than that of the control group (p= 0.001), The post values of the three groups were higher than pre values (p = 0.001).
Conclusion. Both treadmill weight bearing exercises and PEMFs were effective in improving the BMD. Moreover, the BMD response to PEMFs was better than treadmill weight bearing exercise.

Key words:
Bone mineral density, weight bearing exercise, pulsed electromagnetic field, breast cancer, aromatase inhibitors

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