Abstract

Purpose. This study was designed to investigate the effect of life style modification on premenopausal uterine fibroids. Materials and methods. Forty pre-menopausal women diagnosed as uterine fibroids shared in this study. They were selected randomly from the Out-patient clinic of gynecology department in Damanhour Medical National Institute in Damanhour. Their ages were ranged from 36-47 years old. Their body mass index (BMI) didn’t exceed 35 kg/m2. They were diagnosed as subserosal and intramural uterine fibroids. Pregnant women, patients with malignant disease, cardiac pacemakers, myomectomy, psychological problems, postmenopausal patients or hormonal replacement therapy are excluded from study. The design of study was pre-test post-test experimental design. They were divided into two equal groups: Group A (Control group) consisted of 20 patients who received moderate restricted Mediterranean diet for six months. Group B (Study group) consisted of 20 patients who treated by lifestyle intervention program in the form of moderate restricted Mediterranean diet and aerobic exercises (5 times /week) for six months. Each patient in both groups was asked to take 3-4 teabag of Lipton green tea per day. Body mass index (BMI) was assessed by using standard weight-height scale, waist circumference (WC) was assessed by tape measurement; severity of symptoms was assessed by symptoms severity scale questionnaire (SSS) for all patients in both groups A and B before and after treatment. Serum Estradiol (E2), total cholesterol (TC) and triglyceride (TG) were assessed for all patients in both groups A and B before and after treatment. Results. pretreatment, there was no statistical significant difference between both groups A and B in the mean values of BMI, waist circumference, symptoms severity subscale (SSS), serum estradiol (E2), total cholesterol (TC) and triglyceride level (TG). While post treatment, there was statistical significant difference between both groups A and B in the mean values of BMI, waist circumference, symptoms severity subscale (SSS), serum estradiol (E2), total cholesterol (TC) and triglyceride level (TG) (more decrease in group B). Conclusion. Life style modification through aerobic exercise and Mediterranean diet is effective in reducing severity of symptoms and improve quality of life in premenopausal uterine fibroids patients.

Key words:

Life style, Premenopausal, Uterine fibroid, Exercise