Effect of Aerobic Training on Muscle Performance and Quality of Life in Patients with Multiple Sclerosis. A Randomized Controlled Trial

Gehan M. Ahmed, Ebtesam M. Fahmy, Mohamed F. Ibrahim, Amina Awad

Gehan M. Ahmed, Ebtesam M. Fahmy, Mohamed F. Ibrahim, Amina Awad – Effect of Aerobic Training on Muscle Performance and Quality of Life in Patients with Multiple Sclerosis. A Randomized Controlled Trial. Fizjoterapia Polska 2020; 20(5); 174-181

DOI: https://doi.org/10.56984/8ZG2084A3

Abstract
Background. Compromised muscle performance is common problem in multiple sclerosis (MS) patients and subsequently affects activities of daily living and quality of life (QoL). Objective. to investigate the additional effect of short-term aerobic training on both of muscle performance and QoL in patients with MS. Design. Single blinded, parallel randomized controlled trial. Setting. Faculty of Physical Therapy, Cairo University, Egypt. Participants: 40 patients with relapsing remitting MS (RRMS) were randomly divided into two equal groups; intervention (n = 20) and control (n = 20) groups. Intervention. Both groups received a therapeutic exercise program of active strengthening and stretching exercises for selected lower limbs muscles. Only intervention group received aerobic training using bicycle ergometer three sessions weekly for eight successive weeks. Outcomes measures: isokinetic dynamometer parameters; total work, power and fatigue index, to evaluate muscle performance. The Short Form health survey (SF-36) was also applied to evaluate the QoL. Results. Intervention group showed a remarkable significant improvement in all of the isokinetic parameters and in several subscales of SF-36 questionnaire as well when compared with the control group (p < 0.05). Conclusion. adding aerobic training to physical therapy program can be more beneficial in improving muscle performance and quality of life in patients with MS.
Key words:
Aerobic training, Muscle performance, Quality of life, Multiple sclerosis
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Influence of Vestibular Rehabilitation on Balance and Dual-Task Cost of Walking in Patients with Multiple Sclerosis: A Randomized Controlled Trial

Bassam A. El-Nassag, Amina Awad

Bassam A. El-Nassag, Amina Awad – Influence of Vestibular Rehabilitation on Balance and Dual-Task Cost of Walking in Patients with Multiple Sclerosis: A Randomized Controlled Trial. Fizjoterapia Polska 2020; 20(3); 84-89

DOI: https://doi.org/10.56984/8ZG1406E7

Abstract
Background. Balance dysfunction and high dual-task costs are eminent features in multiple sclerosis (MS). Vestibular rehabilitation therapy (VRT) proved to promote functional outcomes; yet, its influence on dynamic balance and dual-task cost of walking (DTCW) in MS needs further research.
Objective. To investigate the effect of adding VRT to aerobic training on dynamic balance and DTCW in people with MS.
Design. Single blinded, parallel randomized controlled trial.
Settings. Out-Patient Clinic at Faculty of Physical Therapy and Kasr Al-Ainy Multiple Sclerosis Unit, Cairo University, Egypt.
Participants. 40 patients with remitting-relapsing multiple sclerosis.
Intervention. Patients were randomized to a control (n = 20) and intervention (n = 20) groups. Over four successive weeks, all patients received stationary bicycle aerobic training. Intervention group received an additional VRT program.
Outcomes measures. Berg Balance Scale (BBS), walking speed tested by the 10 meters timed walk test (10 m-TWT), (DTCW), and overall stability index (SI).
Results. Intervention group showed a remarkable improvement in BBS (p = 0.02), SI at levels four (p = 0.002) and seven (p = 0.03), and DTCW (p = 0.03) compared with control group. Walking speed did not show significant changes post-treatment within or between groups comparison (P > 0.05).
Conclusion. Adding VRT to aerobic training has a positive effect on dynamic balance and dual-task cost of walking in MS.
Key words:
Multiple sclerosis, vestibular rehabilitation, dynamic balance, dual task cost of walking
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